Home (v1) — EndoSphere

Clinical-stage med-device company with a novel
"Endo-Metabolic" device platform for non-invasively treating obesity

Pioneering Endo-Metabolic Devices for Obesity

Using the body’s Natural Physiology to amplify Satiety

EndoSphere has developed a new category of non-invasive endoscopic medical devices for treating obesity using the body’s natural physiology by focusing on the Duodenum, the upper intestinal organ which functions the body’s “metabolic control center”. We call this new category “Endo-Metabolic” devices. We believe this new platform of devices will help to address the recognized limitations of existing obesity therapies (restrictive devices, malabsorption devices, and bariatric surgeries) and will help to transform the way metabolic diseases are treated in the future, starting with Obesity.

Success Stories

“Whatever it is, the way you tell your story online can make all the difference.”

— Quote Source

Founder’s Story

Kenneth Binmoeller, MD
**An accomplished innovator and respected leader in the field**
Kenneth Binmoeller, MD is among the most published researchers and key opinion leaders in the fields of gastroenterology and endoscopy, having authored more than 300 research papers, articles and books.
An accomplished entrepreneur, Dr. Binmoeller’s first start-up Xlumena was acquired by Boston Scientific for $75 million.
**Dr. Binmoeller recognized the huge unmet market need for a new and smarter approach for treating obesity that works with human physiology.**

How the EndoSphere System works

**Endoscopic insertion of device**
The device is inserted to float within the Duodenum because that organ is widely recognized as the body’s Metabolic Control Center.
**Recalibration of the Duodenum**
At its core, the EndoSphere System amplifies Satiety feedback loops by recalibrating the Duodenum to respond faster and longer to food intake. This accelerates Satiety, thereby reducing appetite and slowing digestion.
**Removal of device**
EndoSphere’s device is endoscopically removed in a matter of minutes.

Obesity: A Costly Global Epidemic

Worldwide obesity has nearly tripled since 1975. Most of the world's population lives in countries where obesity and its co-morbidities are a leading cause of death.